Slu7 and cancer
Webb2 nov. 2024 · Finally, we discuss the implications of SLU7 in pathophysiology, with particular emphasis on the progression of liver disease and its possible role as a therapeutic target in human cancer ... Webb23 apr. 2024 · SLU7 knockdown results in R-loops formation, DNA damage, cell-cycle arrest and severe mitotic derangements with loss of sister chromatid cohesion (SCC). We …
Slu7 and cancer
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Webb23 apr. 2024 · This unique function of SLU7 was found in cancer cells of different tissue origin and also in the normal mouse liver, demonstrating a conserved and fundamental role of SLU7 in the... Webb23 apr. 2024 · The research by Wang et al. [12] confirmed that improving SLU7 protein in mice can alleviate liver injury, while the research by Jimenez [13] et al. showed that SLU7 …
Webb8 sep. 2016 · Together, these findings indicate that SLU7 is co-opted by HCC cells and other tumor cell types to maintain survival, and identify this splicing regulator as a new … Webb23 apr. 2024 · The research by Wang et al. [12] confirmed that improving SLU7 protein in mice can alleviate liver injury, while the research by Jimenez [13] et al. showed that SLU7 is crucial to maintain...
WebbSLU7 Gene - Somatic Mutations in Cancer Gene GRCh38 · COSMIC v97 Gene view The gene view histogram is a graphical view of mutations across SLU7. These mutations are displayed at the amino acid level across the full length of the gene by default. WebbScale bars, 200 μm. (c) NAC treatment protected HepG2 and PLC/PRF/5 against SLU7 knockdown-induced autophagy and apoptosis, ... Resisting death is a central hallmark of cancer cells.
WebbTogether, our findings indicate that SLU7 is co-opted by some types of tumors to avoid apoptosis through the regulation of miR-17-92 oncogene; and therefore, this splicing …
Webbal., 2002), including cancer (Hastings and Krainer, 2001; Modrek and Lee, 2002; Stoilov et al., 2002). The splicing protein Slu7 (Frank and Guthrie, 1992) (synergistic lethal with U5 snRNA) and its human homolog hSlu7 (Chua and Reed, 1999a) have been shown to play important roles in 3′ss selection during step two of splicing. inc loftWebb16 nov. 2024 · This unique function of SLU7 has been observed in cancer cells and the livers of normal mice, demonstrating the conserved and essential role of SLU7 in … include computer sound とはWebb21 mars 2024 · SLU7 (SLU7 Homolog, Splicing Factor) is a Protein Coding gene. Diseases associated with SLU7 include Alcoholic Gastritis and Non-Syndromic X-Linked Intellectual Disability.Among its related pathways … inc live streamingWebbSLU7. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … include command in pythonWebbExpression of SLU7 (9G8) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. include common header file htmlWebbExpression of SLU7 (9G8) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability … include computer sound ms teamsWebbSpecifically, SLU7 has been implicated in the epigenetic remodeling of DNA, in the modulation of the transcriptional activity and in controlling protein stability. All these findings identify... include condition in sort