Web16 Aug 2016 · A terpene cyclase from Streptomyces pristinaespiralis was characterized as the synthase for (+)-(2S,3S,9R)-pristinol. The structure of this sesquiterpene alcohol, which has a new carbon skeleton, was established by NMR spectroscopy and single-wavelength anomalous-dispersion X-ray crystallography. Web24 Aug 2024 · Terpene cyclases (TCs), the extraordinary enzymes that create the structural diversity seen in terpene natural products, are traditionally divided into two classes. Although the structural and mechanistic features in class I TCs are well-known, the corresponding details in class II counterparts have not been fully characterized.
A terpene cyclase from Aspergillus ustus is involved in the ...
Web13 Jul 2024 · More evidence to support this mechanism is from the identification of PTTSs producing acyclic products. These PTTSs might have evolved from a cyclic terpene-producing progenitor. A similar scenario has been proposed for typical plant TSs. The ancestral plant TS was probably a cyclase from which acyclic terpene producing enzymes … Web20 Feb 2024 · In this study, we explored the function of a putative terpene cyclase, CcPtc1, and confirmed its ability to regulate pathogenicity, fungal development, and toxic … clinging shellfish creature
Structural biology and chemistry of the terpenoid cyclases.
Web23 Jan 2024 · En route to terpene natural products utilizing supramolecular cyclase mimetics. Qi Zhang a, Lorenzo Catti b, Leonidas-Dimitrios Syntrivanis c and Konrad Tiefenbacher * cd a Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, China b Laboratory for Chemistry and … Web7 Aug 2024 · Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic... WebNovozymes. Jan 2007 - Jun 202414 years 6 months. Davis, California, United States. Almost 15 years of Fungal Molecular biology experience … clingingsmith